This is one of those few comics on the site that don't actually relate to the proper overall canon. I hope that doesn't mean you like it any less!
The reason this particular comic gets to be included in the Best Of is the charming dialogue in the fifth panel, it just warms my heart to think of those ancient ancestors basking in the glow of the semiotic dawn. And saying funny things.
I wonder where that whole caveman outfit cliche came from? The single-strap fur? It's really unflattering.